Let’s make biology engineerable. Together.

We are for the system thinkers. The creative scientists. The fearless builders. These are the bright minds we hire and nurture at Differential Bio. Join us. Be Differential.

Vision

Where Biology Meets Computation

Biology,
engineered.

We are building the computational backbone that will define the future of applying BioAI to regenerative manufacturing.

From experiments
to predictions.

Our platform complements trial-and-error with predictive, digital-first experimentation—faster, cheaper, and smarter.

Enabling the future of biomanufacturing.

Biomanufacturing will define how we produce food, medicine, and materials—and we’re paving the way from lab to market.

Team

We are Differential

Martin is Differential Bio’s technical co-founder, leading the development of our robotic lab automation and AI infrastructure. An expert in AI and autonomous systems, Martin brings deep experience from Recogni, where he helped scale cutting-edge technology from concept to real-world deployment. At Differential, he ensures our platform evolves continuously—intelligent, automated, and built to scale.

Martin Patz

Chief Technology Officer & Co-Founder

Konstantin merges a fresh perspective from his finance and computer science studies, combined with experience at Stanford, with hands-on exposure to the biotech world—from the YC-funded startup Invitris to the innovation ecosystem at Nucleate. At Differential Bio, he drives strategic and operational initiatives at the intersection of science, technology, and execution.

Konstantin Amm

Founder’s Associate

Dong is Differential Bio’s scientific co-founder, driving the biological innovation behind our digital twins. With deep expertise in microbial fermentation and high-throughput screening, Dong is responsible for the data foundation of our predictive models. Her experience as co-founder of Nosh.Bio ensures our biology is grounded, scalable, and built for real-world impact.

Dong Zhao

Chief Science Officer & Co-Founder

Christian leads Differential Bio’s commercial and partnership strategy, ensuring our platform embeds deeply into real-world biomanufacturing workflows. With a background in bioinformatics and experience scaling venture-backed companies like Y42 and Dialogue from early stage to IPO readiness, he shapes the company’s strategic vision and drives its mission to build foundational infrastructure for the bioeconomy.

Christian Spier

Chief Executive Officer & Co-Founder

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Christian Spier

Founder

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Christian Spier

Founder

Values

Built Differential, By Design

Every minute counts.

We act with urgency and strive for excellence. Because our planet depends on us.

Growth mindset.

We operate at the edge of what we know and require a culture of continuous learning.

Eyes on the prize.

We prioritize ruthlessly. We disagree and commit. Striving towards a common goal.

Radical candor.

We are direct with best intentions in mind.

Be yourself.

We are our authentic selves and take care of each other.

Benefits

The Company We’re Building — Together

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Christian Spier

Founder

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aenean quis dictum odio. Sed lobortis feugiat nunc, eget volutpat lorem viverra quis. Etiam laoreet dapibus ex, ac facilisis neque ornare vel. Vestibulum fermentum aliquam purus, nec cursus risus convallis tristique. In faucibus venenatis ligula, consectetur posuere dui hendrerit vel.

Christian Spier

Founder

Get in early.

Join at the ground level of a mission-driven company shaping the future of biomanufacturing through data and AI, unlocking the $4T bioeconomy.

Meaningful ownership.

Competitive compensation through salary and stock options—we’re building a small but mighty team, and we offer compensation to reflect that.

Leadership from day one.

Work directly with the visionary founder team and grow into a role with real responsibility and decision-making power

Work in and around Munich.

A state-of-the-art lab at the Technical University of Munich in Freising and a beautiful Munich office—designed for science, built for collaboration.

Nurture physical & mental health.

We offer benefits that help you recharge
physically and mentally, like access to eGym WellPass.

Hiring Process

Tech-, mindset-, mission-aligned

Step One

Screening

Kick things off with a 30-minute intro call with the team. We’ll learn your story, share what we’re building, and explore the strong mutual fit.

Step Two

Deep Dive

Roll up your sleeves and dive into the role. You’ll tackle a practical case with us, exchange ideas, and show your approach to real-world challenges.

Step Three

Personal Fit & Offer

Meet the team and feel our culture. It's your chance to experience the Differential personality. We’ll wrap up with two 15-minute calls and quick reference checks.

Open Roles

Join an early team
with a big mission

Engineering

Member of Technical Staff - AI Research

New York

Member of Technical Staff - AI Research

New York

Member of Technical Staff - Infrastructure

New York

Member of Technical Staff - Product Engineering

New York

Member of Technical Staff - Security

New York

Senior Product Engineer

New York

General

General Application

New York

GTM & Growth

Head of Marketing

New York

Sales Engineer

New York

People

Office Manager

New York

Product & Design

Clinician Scientist

New York

Design Engineer

New York

Designer That Can Code

New York

Frontier Strategist

New York

About Us

Life at Differential

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